Semi Prep HPLC Column, NP Amino, 10um, 100A. 10mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Amino is a versatile normal phase and HILIC stationary phase designed for retention of highly polar compounds that are often difficult to retain using conventional reversed-phase columns. Manufactured on high-purity silica with a propyl amino bonded phase, it provides excellent selectivity for carbohydrates, sugars, organic acids, and other polar analytes. This stationary phase is commonly used as an alternative for USP L8 methods and is suitable for both Normal Phase and HILIC separations.
68040-SP50 is a semi-preparative HPLC column packed with 10 µm NP Amino particles featuring a 100 Å pore size in a 10 mm ID x 50 mm format. The larger internal diameter provides increased sample loading capacity compared to analytical columns while maintaining efficient chromatographic performance. The short 50 mm length is optimized for rapid method development, purification screening, and analytical-to-preparative method transfer. Typical operating flow rates are approximately 8–15 mL/min depending on mobile phase composition, sample load, and system configuration.
This column is particularly effective for sugars, carbohydrates, negatively charged compounds, organic acids, carboxylic acid-containing compounds, and other highly polar molecules. As with all amino phases, this column is suitable for both Normal Phase and HILIC applications when enhanced retention of polar analytes is required.
Key Benefits
NP Amino stationary phase
USP L8 equivalent chemistry
Propyl amino bonded phase
High-purity silica support
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Enhanced retention of polar compounds
Excellent for sugars and carbohydrates
Low operating backpressure with 10 µm particles
Ideal for semi-preparative method development and purification scouting
Typical Applications
Semi-preparative chromatography
USP L8 methods
HILIC separations
Normal Phase chromatography
Sugar purification
Carbohydrate purification
Organic acid analysis and purification
Carboxylic acid separations
Pharmaceutical purification
Method scale-up from analytical columns
Specifications
Product Type: Semi Prep HPLC Column
Stationary Phase: NP Amino
USP Classification: L8
Chromatography Mode: Normal Phase / HILIC
Bonded Phase: Propyl Amino
Endcapping: Not Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 10 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 8–15 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Packed and shipped in Normal Phase solvents
Suitable for both Normal Phase and HILIC chromatographic modes
Excellent retention of sugars, carbohydrates, and organic acids
Short column length is ideal for rapid method development and purification scouting
Ideal for semi-preparative purification and analytical-to-prep method scale-up
Requires an HPLC system capable of supporting semi-preparative flow rates of approximately 8–15 mL/min
This is a Special Order Item